Preheat oven to 350 degrees F. Spray a 9-inch pie plate with olive oil.
Place the spinach in a microwave-safe bowl. Add 1/2 cup water. Cover and microwave until thawed, about 4 minutes. Allow to slightly cool, then place the thawed spinach in a clean kitchen towel and squeeze hard to get rid of excess liquid.
In a large bowl, whisk together the eggs, yogurt, kosher salt, pepper, garlic powder, onion powder and Parmesan. Stir in the spinach.
Pour the mixture into the prepared pie plate. Bake until quiche is puffed, its edges are browned and its center appears set, and a toothpick inserted in its center comes out clean, about 40 minutes.
Cool 20 minutes in the pan on a cooling rack before slicing.