Preheat your oven to 350° F. Line a sheet pan with foil (for easy cleanup) and grease the foil.
In a medium bowl, whisk together the egg, salt, pepper, garlic powder, onion powder, and smoked paprika.
Add the ground beef, almond flour and Parmesan. Gently mix, just until uniform.
Divide the beef mixture into two halves. Form one half into a roughly 8-by-4-inch rectangle (you can use a clingwrap-lined loaf pan as your mold, as shown in the video below) and place the rectangle on the prepared baking sheet. Place the hard boiled eggs, evenly spaced, on top.
Place the second half of the beef mixture on top of the eggs. Press it so that it adheres to the bottom layer. With your fingers, pinch the edges of the two rectangles together, to create one meatloaf. Pinch well, to prevent the meatloaf from bursting at the seams as it bakes. You can transfer pinches of ground beef to sparse areas where eggs are peeking or where it's difficult to pinch the edges together.
Brush the meatloaf with the ketchup.
Bake until the center of the loaf registers 160° F, 50-60 minutes.
Rest the meatloaf for 15 minutes before slicing and serving.